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The principal cytochrome P450 isoenzyme associated appears being CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Around eighty five% of an oral dose appears during the urine within just 24 several hours of administration, most given that the glucuronide conjugate, with little quantities of other conjugates and unchanged drug (see OVERDOSAGE) for

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